Oklahoma State University

Department of Nutritional Sciences

Metabolic and Nutrition Phenotyping Core Facility

Metabolic and Nutrition Phenotyping Core Facility:

Body Composition, Bone Mineral Density, and Trace Element Analysis

Spectroscopy

The Department of Nutritional Sciences Core Facility houses equipment available for use (with user fees) to researchers across OSU campuses. 

Hologic Discovery A QDR 4500 Series Dual-energy X-ray Absorptiometers (DXA):) DXA is the industry standard for measuring both human and animal bone density, but is also a valuable tool for assessing body composition (lean body mass and adipose). Currently, the Department of Nutritional Sciences houses two state-of-the-art Hologic DXA’s (same model, however, one with a 300 lb. weight limit; the newer one with a 450 lb. weight limit) which are utilized by researchers in the department, in addition to other departments on campus, to determine the effects of dietary and environmental factors on bone mineral density.
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Scanco Medical mCT 40: This mCT unit is designed to scan small bone specimens (i.e., rodent or larger animal biopsies) to create a three-dimensional model without damaging the original biological specimen.  The mCT is used in the Department to examine the effects of various physiological conditions (i.e., hormone or nutrient deficiencies) on bone microarchitecture. Specimens can be scanned both in the absence of presence of solution (i.e., formalin fixative). Departmental faculty members provide analytical services to other investigators across campus to assess the structural and biomechanical properties of bone.
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Lunar Piximus: This pencil-beam DXA allows for the determination of bone mineral density and body composition of small animal models (i.e., Mus musculus).
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Perkin-Elmer Elan 9000 Inductively Coupled Plasma-Mass Spectrometer (ICP-MS): ICP-MS is a highly sensitive method useful for determining amounts of beneficial or toxic trace elements that may be present only in the parts per billion range.  ICP-MS can be used for the elemental analysis of both biological (e.g., blood or urine) and environmental (e.g., water) samples. The Department of Nutritional Sciences is currently utilizing ICP-MS analysis to measure trace minerals in blood, serum, and food, but it can also be used for mineral and isotope analyses of environmental samples (e.g., water or soil samples).
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For more general information regarding available equipment and services, please contact:
Sandra Peterson, Lab Manager
Department of Nutritional Sciences
415 Human Sciences
(405) 744-3003