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Oklahoma State University

Dingbo (Daniel) Lin

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Assistant Professor

419 Human Sciences
Stillwater, OK 74078
Phone: (405)744-5215
Fax: (405)744-1357

dingbo.lin@okstate.edu

Education

Degree Institution Area of Study
Ph.D. Zhejiang University, Hangzhou, China Biochemistry
M.S. Shanxi Agricultural University, Taigu, China Plant Physiology and Biochemistry
B.S. Zhejiang A & F University, Linan, China Forestry

Expertise

Interplay of microbiome-carotenoid metabolism; Mitochondrial function and energy metabolism; Oxidative stress and chronic inflammation; Diabetes and infectious disease

Publications

Book Chapter

At Oklahoma State University

  • Hua Ji, Hui He, Dingbo Lin. 2014. Dietary wolfberry and retinal degeneration. In: Victor R. Preedy (editor-in-chief, King’s College London), Handbook of Nutrition, Diet, and the Eye. pp465-472 (Chapter 47). Elsevier Inc. (Academic Press)
  • Lei Wu, Dingbo Lin. 2019. Molecular aspects of carotenoid metabolizing enzymes and implications for ophthalmology. In: Ronald R. Watson and Victor R. Preedy (editor-in-chief), Handbook of Nutrition, Diet, and the Eye, 2nd edition (invited chapter, in press) 

Refereed Publications

At Oklahoma State University

  • Yi Lyu, Lei Wu, Fan Wang, Xinchun Shen, Dingbo Lin. 2018. Carotenoid supplementation and retinoic acid in regulation of immunoglobulin A production and gut microbiome dysbiosis. Exp Biol Med. 2018, 243:613-620
  • Yali Yu, Yao Wang, Ying Wang, Dingbo Lin, Jingbo Liu. 2018. Preparation and properties of granular cold-water-soluble maize starch by ultrasonic assisted alcoholic-alkaline treatment. Starke-Starch. (Accepted)
  • Yali Yu, Xiaomeng Sun, Haiqing Ye, Jingbo Liu, Lei Wu, Dingbo Lin, Feng Gao. 2018. Assessment of anti-diabetic activity of peanut shell polyphenol extracts in high-fat diet/streptozotocin-induced type 2 diabetic rats. J Zhejiang Univ-Sci B. (Accepted)
  • Lei Wu, Xin Guo, Yi Lyu, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith, Deana Hildebrand, Weiqun Wang, Denis M. Medeiros, Xinchun Shen, Dingbo Lin. 2017. Targeted metabolomics reveals abnormal hepatic energy metabolism by depletion of β–carotene oxygenase 2 in mice. Scientific Reports 2017 Nov 7;7(1):14624. doi: 10.1038/s41598-017-15222-x.
  • Jun Huang, Yiwei Zhang, Lin Dong, Qinghan Gao, Lei Yin, Hongfeng Quan, Rong Chen, Xueyan Fu, Dingbo Lin. 2018. Ethnopharmacology, phytochemistry, and pharmacology of Cornus officinalis Sieb. Et Zucc.J Ethnopharmacol. 2018, 213:280-301 
  • Shiya Hua, Yiwei Zhang, Jiayue Liu, Lin Dong, Jun Huang, Dingbo Lin, Xueyan Fu. 2018. Ethnomedicine, phytochemistry and pharmacology of Smilax glabra: An important traditional Chinese Medicine. Am J Chin Med. 2018, 46(2):261-297
  • Jinlong Wu, Wenjun Deng, Dingbo Lin, Xiuxin Deng, Zhaocheng Ma. An immunoblotting quantification approach for identifying potential hypoallergenic citrus cultivars. J Agric Food Chem. 2017. (Accepted)
  • Jennifer L. Graef, Elizabeth Rendina-Ruedy, Erica K. Crockett, Ping Ouyang, Lei Wu, Jarrod B. King, Robert H. Cichewicz, Dingbo Lin, Edralin A. Lucas, Brenda J Smith. 2017. Osteoclast differentiation is downregulated by select polyphenolic fractions from dried plum via suppression of MAPKs and Nfatc1 in mouse C57BL/6 primary bone marrow cells. Current Developments in Nutrition. (Accepted)
  • Yali Yu, Lijun Wang, Ying Wang, Dingbo Lin, Jingbo Liu. 2017. Hepatoprotective effect of albumin peptides from corn germ meal on chronic alcohol-induced liver injury in mice. J Food Sci. 2017 Oct 30. doi: 10.1111/1750-3841.13953.
  • Liping Cheng, Yujie Ren, Dingbo Lin, Shu’ang Peng, Bo Zhong, Zhaocheng Ma. 2017. The anti-inflammation properties of Citrus wilsonii Tanaka extracts in LPS-induced RAW264.7 and primary mouse bone marrow-derived dendritic cells. Molecules. 2017 Jul 19;22(7). pii: E1213. doi: 10.3390/molecules22071213.
  • Babajide Ojo, Ashley J Simenson, Crystal O’Hara, Lei Wu, Xin Guo, Sandy Peterson, Dingbo Lin, Brenda J Smith, Edralin A Lucas. 2017. Wheat germ supplementation alleviates insulin resistance and cardiac mitochondrial dysfunction in an animal model of diet-induced obesity. Br J Nutr. 118(4):241-249
  • Xin Guo*, Lei Wu*, Yi Lyu, Winyoo Chowanadisai, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith, Hui He, Weiqun Wang, Denis M Medeiros, Dingbo Lin. 2017. Ablation of β,β-carotene -9’, 10’-oxygenase 2 remodels the hypothalamic metabolome leading to metabolic disorders in mice. J Nutr Biochem. 46:74-82
  • Hongjing Wang, Liping Cheng, Dingbo Lin, Zhaocheng Ma, Xiuxin Deng. 2017. Lemon fruits lower the blood uric acid levels in humans and mice. Sci Hortic. 220: 4-10 
  • Siyuan Chen, Dingbo Lin, Yulong Gao, Xiaozhou Cao, Xinchun Shen. 2017. A novel antioxidant peptide derived from wheat germ prevents high glucose-induced oxidative stress in vascular smooth muscle cells. Food & Function. 8(1):142-150
  • Yuting Wang, Dingbo Lin, Xiaoli Wang, Wei Zhu, Junli Ye, Guohuai Li, Zhaocheng Ma, Xiuxin Deng. 2016. The impact of a novel peach gum-derived polysaccharide on postprandial blood glucose control in streptozotocin-induced diabetic mice. Intl J Biol Macromol. 98:379-386
  • Lei Wu, Xin Guo, Steven Hartson, Abby Davis, Hui He, Denis M Medeiros, Weiqun Wang, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith, Johannes von Lintig, Dingbo Lin. 2016. Lack of β,β-carotene -9’, 10’-oxygenase leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice. Mol Nutr Food Res. DOI: 10.1002/mnfr.201600576. [Epub ahead of print]
  • Jinlong Wu, Lin Chen, Dingbo Lin, Zhaocheng Ma, Xiuxing Deng. 2016. Development and application of a multiplex real-time PCR assay as an indicator of potential allergenicity in citrus fruits. J Agric Food Chem. 64(47):9089-9098.
  • Lei Wu, Xin Guo, Wenqun Wang, Denis M Medeiros, Stephen L Clarke, Edralin A Lucas, Brenda J Smith, Dingbo Lin. 2016. Molecular aspects of β, β-carotene-9’, 10’-oxygenase 2 in carotenoid metabolism and diseases. Exp Biol Med. 241(17):1879-1887
  • Xin Guo, Lei Wu, Weiqun Wang, Denis M Medeiros, Stephen Clarke, Edralin Lucas, Brenda J Smith, Winyoo Chowanadisai, Dingbo Lin. 2016. Hypothalamic mitochondria in energy homeostasis and obesity. Integrative Molecular Medicine. 3(2):590-599. DOI: 10.15761/IMM.1000209
  • Haizhao Song, Tao Wu, Dongdong Xu, Qiang Chu, Dingbo Lin, Xiaodong Zheng. 2016. Dietary sweet cherry anthocyanins attenuate diet-induced hepatic steatosis by improving hepatic lipid metabolism in mice. Nutrition. 32 (7-8): 827-833
  • Ramila Azat, Yan Liu, Abdurihim Kayir, Dingbo Lin, Wenwen Zhou, Xiaodong Zheng. 2016. Probiotic properties of lactic acid bacteria isolated from traditionally fermented Xinjiang cheese. J Zhejiang Univ-Sci B (Biomed & Biotechnol). 17(*):597-609. DOI: 10.1631/jzus.B1500250
  • Jessica Berg, Dingbo Lin. 2014. Lutein and zeaxanthin: an overview of metabolism and eye health. J Human Nutr Food Sci. 2(4): 1039
  • Xueyan Fu,Yu Huang,Xiaolan Kang, Tingting Li, Xin Jia, LinDong,Lei Wu, Dingbo Lin. 2014. The wolfberry bud tea has enhanced antioxidant activities.Austin J Nutr Food Sci.2(3):5.
  • Dingbo Lin, Hui He, Hua Ji, Jordan Willis, Lloyd Willard, Yu Jiang, Denis M Medeiros, Logan Wark, Jing Hang, Yongzhang Liu, Bin Lu. 2014. Wolfberries potentiate mitophagy and enhance mitochondrial biogenesis leading to prevention of hepatic steatosis in obese mice: the role of AMP-activated protein kinase α2 subunit. Mol Nutr Food Res. 58:1005-1015 

At Kansas State University

  • Huifeng Yu, Jin Han, Logan Wark, Lloyd Willard, Hui He, Edlin Ortiz, Yunong Zhang, Hua Ji, Denis M Medeiros, Dingbo Lin. 2013. Dietary wolfberry up-regulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice. Mol Nutr Food Res. 57:1158-1169
  • Yu Jiang, Haitian Ma, Xiaoyu Su, Jie Chen, Joseph Standard, Dingbo Lin, Weiqun Wang. 2012. IGF-1 mediates exercise-induced phospholipid alteration in the murine skin tissues. J Nutr Food Sci. 2012, S2
  • Ling Tang, Yunong Zhang, Yu Jiang, Lloyd Willard, Edlin Ortiz, Logan Wark, Denis Medeiros, Dingbo Lin. 2011. Dietary wolfberry ameliorates retinal structure abnormalities in db/db mice at the early stage of diabetes. Exp Biol Med. 236:1051-1063
  • Jean Getz, Dingbo Lin, Denis M Medeiros. 2011. The cardiac copper chaperone proteins Sco1 and CCS are up-regulated, but Cox 1 and Cox4 are down-regulated, by copper deficiency. Biol Trace Elem Res. 143(1):368-377
  • Yu Jiang, Yunong Zhang, Logan Wark, Edlin Ortiz, Soyoung Lim, Hui He, Weiqun Wang, Denis Medeiros, Dingbo Lin. 2011. Wolfberry water-soluble phytochemicals down-regulate ER stress biomarkers and modulate multiple signaling pathways leading to inhibition of proliferation and induction of apoptosis in Jurkat cells. J Nutr Food Sci. 2011 Nov 24;S2. Pii:001
  • Allan Ayella, Soyoung Lim, Yu Jiang, Takeo Iwamoto, Dingbo Lin, John Tomich, Weiqun Wang. 2010. Cytostatic inhibition of cancer cell growth by lignin secoisolariciresinol diglucoside. Nutr Res. 30:762-769
  • Denis M Medeiros, Yu Jiang, Darcey L Klaahsen, Dingbo Lin. 2009. Mitochondrial and sarcoplasmic protein changes in hearts from copper-deficient rats: Upregulation of PGC1-α transcript and protein as a cause of mitochondrial biogenesis in copper deficiency. J Nutr Biochem. 20:823-830
  • Vladimir V Yevseyenkov, Satyabrata Das, Dingbo Lin, Lloyd Willard, Harry Davidson, Ali Sitaramayya, Frank J Giblin, Loan Dang, Dolores J Takemoto. 2009. Loss of protein kinase Cgamma in knockout mice and increased retinal sensitivity to hyperbaric oxygen. Arch Ophthalmol. 127:500-506
  • Yunong Zhang, Adam Snider, Lloyd Willard, Dolores J Takemoto, Dingbo Lin. 2009. Loss of Purkinje cells in the PKCgamma H101Y transgenic mouse. Biochem Biophys Res Comm. 378:524-528
  • Satyabrata Das, Dingbo Lin, Snehalata Jena, Aibin Shi, Srinivas Battina, Duy H Hua, Rachel Allbaugh, Dolores J Takemoto. 2008. Protection of retinal cells from ischemia by a novel gap junction inhibitor.  Biochem Biophys Res Comm. 373: 504-508
  • Michael Barnett, Dingbo Lin, Vladimir Akoyev, Lloyd Willard, Dolores J Takemoto. 2008. Protein kinase C epsilon activates lens mitochondrial cytochrome C oxidase Subunit IV during hypoxia. Exp Eye Res. 86:226-234
  • Dingbo Lin*, Dolores J. Takemoto. 2007. Protection from ataxia-linked apoptosis by gap junction inhibitors. Biochem Biophys Res Comm. 362:982-987  *corresponding author
  • Dingbo Lin, Guido A. Zampighi, Dolores J. Takemoto. 2007. Protein kinase C gamma activation in the early streptozotocin-diabetic rat lens. Current Eye Res. 32:523-532
  • Dingbo Lin, Denton Shanks, Om Prakash, Dolores J. Takemoto. 2007. Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions. Exp Eye Res. 85:113-122
  • Dingbo Lin, Michael Barnett, Samuel Lobell, Daniel Madgwick, Guido A. Zampighi,  Dolores J. Takemoto. 2006. PKC gamma knockout mouse lenses are more susceptible to oxidative stress damage. J Exp Biol. 209:4371-4378\Dingbo Lin, Dolores J. Takemoto. 2005. Oxidative activation of protein kinase C gamma through the C1 domain: effects on gap junctions. J Biol Chem. 280:13682-13693
  • Dingbo Lin, Michael Barnett, Jerry Robben, Annie Jewell, Larry Takemoto, Dolores J. Takemoto. 2005.Expression of SOD in the whole lens prevents cataract formation. Mol Vis. 11:853-858
  • Guido A. Zampighi, Ana M. Planells, Dingbo Lin, Dolores J. Takemoto. 2005. Regulation of lens cell-to-cell communication by activation of PKCgamma and disassembly of Cx50 channels. Invest Ophthalmol Vis Sci. 46:3247-3255
  • Dingbo Lin, Sam Lobell, Annie Jewell, Dolores J. Takemoto. 2004. Differential phosphorylation of Cx46 and Cx50 by H2O2 activation of protein kinase C gamma. Mol Vis. 10:688-695
  • Dingbo Lin, Jianzheng Zhou, Peggy Zelenka, Dolores J. Takemoto. 2003. Protein kinase C gamma regulation of gap junction activity through caveolin-1 containing lipid rafts.  Invest Ophthalmol Vis Sci. 44: 5259-5268
  • Dingbo Lin, Daniel J. Boyle, Dolores J. Takemoto. 2003. IGF-1-induced phosphorylation of connexin 43 by PKCgamma: Regulation of gap junctions in rabbit lens epithelial cells. Invest Ophthalmol Vis Sci. 44:1160-1168

 

Presentations

At Oklahoma State University

  • Y Lyu, L Wu, X Guo, A Davis, S Clarke, E Lucas, B Smith, W Wang, Denis M Medeiros, Xinchun Shen, D Lin. Targeted metabolomics Reveals Abnormal Hepatic Energy Metabolism in β, β-Carotene-9′, 10′-Oxygenase 2 Knockout Mice. FASEB Journal 31 (1 Supplement), 655.5-655.5
  • X Shen, Y Lyu, L Wu, D Lin. Astaxanthin mediates mitochondrial dynamics in mice. FASEB Journal 31 (1 Supplement), lb422-lb422
  • L Wu, X Guo, Y Lyu, SL Clarke, EA Lucas, BJ Smith, W Wang, D M Medeiros, X Shen, D Lin. Deficiency of β, β-Carotene-9′, 10′-Oxygenase 2 Links to Systemic Inflammation, Dyslipidemia and Glucose Intolerance. FASEB Journal 31 (1 Supplement), 797.16-797.16
  • TZ Tang, MD Hart, MR Nacke, L Wu, JL Fiddler, SL Clarke, BJ Smith, D Lin, W Chowanadisai. Loss of ZIP12 Leads to Mitochondrial Dysfunction and Reduced Neurite Outgrowth in Neuro-2A Neuroblastoma Cells. FASEB Journal 31 (1 Supplement), 637.8-637.8
  • B Ojo, AJ Simenson, C O’Hara, L Wu, X Gou, SK Peterson, D Lin, BJ Smith, EA Lucas. Wheat germ supplementation alleviates insulin resistance and cardiac mitochondrial dysfunction in an animal model of diet-induced obesity. Experimental Biology, April 2017; Chicago, IL
  • Dingbo Lin, Lei Wu, Xin Guo, Yi Lyu, Stephen Clarke, Edralin Lucas, Brenda J Smith, Deana Hildebrand. Deficiency ofβ,β-carotene-9’,10’-oxygenase 2 links to dyslipidemia and glucose intolerance. Harold Hamm Diabetes Center Research Symposium, Oct. 28, 2016
  • Lei Wu, Xin Guo, Abby Davis, Traces Petchdee Soh, Stephen Clarke, Edralin Lucas, Brenda Smith, Weiqun Wang, Denis Medeiros, Dingbo Lin. Ablation of BCO2 leads to increased susceptibility to high fat diet-induced metabolic disorders in mice. Experimental Biology 2016, San Diego (oral presentation)
  • Xin Guo, Lei Wu, Traces Soh, Winyoo Chowanadisai, Stephen Clarke, Edralin Lucas, Brenda Smith, Weiqun Wang, Denis Medeiros, Dingbo Lin. Altered fatty acid metabolism remodels the hypothalamic metabolome to stimulate feeding behavior in BCO2 knockout mice. Experimental Biology 2016, San Diego (oral presentation)
  • Ojo B, Simenson AJ, O’Hara C, Wu L, Gou S, Peterson SK, Lin D, Smith BJ, Lucas EA. Wheat germ supplementation alleviates insulin resistance and cardiac mitochondrial dysfunction in an animal model of diet-induced obesity. Harold Hamm Diabetes Research Symposium, October 28, 2016, Oklahoma City, OK. Babajide O 1st place winner poster competition
  • Simenson AJ, Ojo B, O’Hara C, McMillen L, Wu L, Gou X, Peterson SK, Lin D, Smith BJ, Lucas EA. Effects of wheat germ supplementation on mitochondrial function in mice fed high-fat diet. Annual Oklahoma State University Research Week, Feb. 2016
  • Dingbo Lin.  Lei Wu. Overnutrition triggers mitochondrial stress leading to obesity. The 1st International Conference on Childhood Obesity and Hypertension, Beijing, China, May 29-31, 2015
  • Dingbo Lin. Proteomic and functional analysis of hypothalamic mitochondria in β,β-carotene-9’,10’-oxygenase 2 (BCO2) knockout mice with a feeding disorder. BIT’s 6th Annual World Congress of Neurotalk-2015, Hangzhou, China, May 22-24, 2015
  • Dingbo Lin. Carotenoid metabolism and mitochondrial dysfunction in obesity. the 12th Chinese Nutrition Sciences Conference, Beijing, China, May 16-18, 2015
  • Lei Wu, Xin Guo, Steve Hartson, Stephen Clarke, Edralin Lucas, Brenda J Smith, Dingbo Lin. Intact β,β-carotene-9’, 10’-oxygenase2 (BCO2) is essential to the integrity of hepatic mitochondrial function in mice. Experimental Biology 2015, Boston (oral presentation)
  • Xin Guo, Lei Wu, Stephen Clarke, Dingbo Lin. Quercetin alters ETC/OXPHOS in isolated hepatic mitochondria. Experimental Biology 2015, Boston (poster presentation)  
  • Babajide Ojo, Lei Wu, Xin Guo, Jessica Semkoff, H Eldoumi, Sandy Peterson, Peter Perkins-Veazie, Dingbo Lin, Brenda J Smith, Edralin Lucas. Mango supplementation averts hepatic and cardiac mitochondrial dysfunction in mice fed a high-fat diet. Experimental Biology 2015, Boston (oral presentation)
  • Babajide Ojo, Lei Wu, Xin Gou, Jessica Semkoff, SJ Janthachotikun, H Eldoumi, Sandy Peterson, P Perkins-Veazie, Dingbo Lin, Brenda J Smith B, Edralin A Lucas. Mango supplementation averts hepatic and cardiac mitochondrial dysfunction in mice fed a high-fat diet. The 22nd OSU Research Symposium, February 2015; Stillwater, OK
  • Katherine Janike, Traces Soh, Joanna Fiddler, Edralin A Lucas, Brenda J Smith, Dingbo Lin, Stephen Clarke. Role of iron in controlling circadian gene expression: Does iron deficiency increases the risk of metabolic disease? The 22nd OSU Research Symposium, February 2015; Stillwater, O
  • Dingbo Lin, Denis Medeiros. Wolfberries potentiate mitophagy in the liver of obese mice. Experimental Biology 2014, San Diego, CA
  • Lei Wu, Xin Guo, Steve Hartson, Stephen Clarke, Edralin Lucas, Brenda J Smith, Dingbo Lin. Functional impact of β,β-Carotene -9’,10’-Oxygenase 2 (BCO2)  in hepatic mitochondria, the 11th Harold Hamm Diabetes Center Research Symposium, OUHSC. 10/2014 (poster presentation)
  • Lei Wu, Xin Guo, Steve Hartson, Stephen Clarke, Edralin Lucas, Brenda J Smith, Dingbo Lin. Functional impact of β,β-carotene-9’,10’-oxygenase 2 (BCO2)  in hepatic mitochondria. 11th BMBGSA Annual Research Symposium, OSU, 09/2014 (oral presentation)
  • Dingbo Lin, Muayyad Al-Baidi. β,β-carotene-9’, 10’ –oxygenase 2 in the diabetic retinal degeneration, OK HH Diabetes Research Center, Oklahoma City, Oct. 25, 2013

At Kansas State University

  • Dingbo Lin. Dietary bioactive compounds on diabetes, obesity, and insulin resistance. The Westlake Frontier in Nutrition Workshop-2013. Invited speaker, Hangzhou, China
  • Dingbo Lin. Dietary zeaxanthin attenuates mitochondrial stress, improves insulin resistance, and protects against retinal degeneration. The International Conference on Food Science and Technology Innovation –FoodInnova-2012, Hangzhou, China
  • Dingbo Lin. Zeaxanthin attenuates mitochondrial stress and inhibits lipoapoptosis of hepatocytes: the role of AMPK.Cold Spring Harbor-Asia 2012, Suzhou, China
  • Dingbo Lin. Dietary wolfberry increases hepatic insulin sensitivity in obese mice. Experimental Biology 2012, San Diego, CA
  • Dingbo Lin. Dietary wolfberry ameliorates retinal structure abnormality through activation of AMP-activated protein kinase signaling in the db/db type 2 diabetic mouse. Experimental Biology 2011, Washington DC
  • Dingbo Lin. Wolfberry supplements prevent the development of hepatic steatosis Experimental Biology 2010, Anaheim, CA
  • Dingbo Lin. Wolfberry water-soluble components selectively induce leukemia cell apoptosis. International Conference on Natural Products and Traditional Medicine  2009, Xi-an, China (Session Chair)
  • Dingbo Lin. Wolfberry water-soluble extracts activate gap junctions in ARPE-19 cells. Experimental Biology 2009, New Orleans, LA
  • Dingbo Lin. Mutations of protein kinase C gamma in spinocerebellar ataxia cause altered cell gap junctional communication in lens epithelial cells. ARVO2005, Ft Lauderdale, FL
  • Dingbo Lin. PKC gamma: Loss of stress sensing activity leads to spinocerebellar ataxia. Ataxia Investigator’s Meeting 2005, Tampa, FL
  • Dingbo Lin. 2004. Protein kinase C gamma mediates regulation of gap junctional communication by H2O2 in the lens. ARVO 2004,Ft. Lauderdale, FL

Courses Taught:

  • Phytochemicals in Reduction of Chronic Disease, NSCI 6033
  • Graduate Seminar, NSCI 5960/6960
  • Micronutrients in Human Nutrition, NSCI 5043
  • Human Nutrition and Metabolism II, NSCI 4143/5353
  • Human Nutrition and Metabolism, NSCI 4323/5333
  • Special Unit Studies in Nutritional Sciences, NSCI 4850
  • Principles of Human Nutrition Honors Discussion, NSCI 2114
  • Advanced Lab Techniques in Nutritional Sciences, NSCI 5743

Awards & Recognition: 

  • Invited Speaker, 2018 Gordon Research Conference on Carotenoids, June 17-22, 2018, Maine
  • Nominee, 2018 OSU Regents Distinguished Teaching Award
  • Nominee, 2018 College of Human Sciences’ Outstanding Graduate Faculty Mentor Award
  • Invited speaker, the 3rd International Symposium on Phytochemicals in Medicine and Foods, Aug. 25-30, 2018, Kunming, China (awarded to cover the travel and meeting costs)
  • Member, Literature Selection Technical Review Committee, NIH/NLM, July 2018-June 2022
  • 2017-2018 Chair, Award Committee, the North America Chinese Society for Nutrition (NACSN)
  • 2017 Nominee for the Literature Selection Technical Review Committee (LSTRC), NLM/NIH (by Dr. Joyce Backus, NLM)
  • 2017 USDA NIFA National Diabetes Awareness Day. We put together a blog, highlighting our USDA NIFA project that is directly addressing health, November 14th, in DC
  • 2017 USDA-AFRI Review Panel for the Program of the Function and Efficacy of Foods
  • 2017 Review Panel for the Prestigious Program of the National Natural Science Foundation of China
  • 2017 Canada Foundation for Innovation – Peer review (CFI37120)- Vitamin A Lab Research Program
  • Organizing Committee Member, World Congress on Food Technology, Dubai, UAE. April 24-27, 2017
  • 2016 USDA-AFRI Review Panel for the Program of the Function and Efficacy of Foods
  • Session Moderator, Harold Hamm Diabetes Center Research Symposium, Oct. 28, 2016
  • Session Co-chair, the first NACSN Symposium April 4, 2016, San Diego, CA
  • Awardee, 2016 OSU College of Human Sciences the Marguerite Scruggs Award for Meritorious Early Career Research
  • Nominee, 2016 American Society for Nutrition the ELR Stokstad Award
  • Invited speaker, the 12th Chinese Nutrition Sciences Conference, Beijing, China, May 16-18, 2015
  • Co-chair, Minisymposium: Aging-Nutrition, physical performance, and bone health. Experimental Biology 2014, San Diego, CA
  • Invited speaker, the first Westlake Frontiers in Nutrition Research Training Program, May 17-19, 2013, Hangzhou, China
  • Travel award and invited speaker, the International Conference on Food Science and Technology Innovation –FoodInnova-2012, December 12-14, Hangzhou, China
  • Session Chair. The International Conference of Natural Products and Traditional Medicine. 2009, Xi-an, China
  • Junior faculty travel grant to the Ataxia Investigator’s Meeting by the National Ataxia Foundation, March 25-28, 2008, Las Vegas, NV
  • National Eye Institute travel award to ARVO2007, Fort Lauderdale, FL
  • Travel fellowship award for the 131st Annual Meeting of the American Neurological Association at the Chicago Hyatt Regency Hotel, Oct. 8-11, 2006
  • Young investigator travel grant to the Ataxia Investigator’s Meeting by the National Ataxia Foundation, March 2-4, 2005, Tampa, FL
  • STA Fellowship (Science and Technology Agency of Japan) from December 1998 to December 2000, Japan

Grants:

Current Funding

  • Conway T (Mentor), Lin D (Mentee). Carotenoid metabolism improves the gut microbiome in type 2 diabetes. OSU VPR Mentor/mentee program, April 1, 2018-June 30, 2019. (Internal competitive university funding)
  • Lin D, Clarke SL, Smith BJ. Watermelon and the bioactive compounds promote the digestive health in diabetes. National Watermelon Promotion Board, April 1, 2018-March 31, 2019. -P.I.
  • Lin D, Clarke SL, Lucas EA, Smith BJ, Park Y. Peach and the bioactive polysaccharides protect gut microbiota against diabetes. Oklahoma Agricultural Experiment Station. 1, 2017-July 31, 2019. -P.I. (Internal competitive university funding)
  • Lin D, Clarke SL, Chowanadisai W, Narasaraju T, Liu L. β,β-carotene 9’, 10’-oxygenase 2 (BCO2) in acute respiratory distress syndrome. OCAST HR17-114, July 1, 2017-June 30, 2020. -P.I.

Completed Funding

  • Lin D, Clarke SL, Lucas EA, Smith BJ, Ramanathan R. Egg xanthophylls prevent chronic inflammation in type 2 diabetes. USDA NIFA, Mar. 1, 2015-Feb. 28, 2018. -P.I.
  • Lin D, Clarke SL, Lucas EA, Smith BJ, Hildebrand D. β,β-carotene 9’, 10’-oxygenase 2 impacts hepatic mitochondrial function in obesity. Oklahoma Agricultural Experiment Station/USDA Hatch project. 1, 2015-July 31, 2017. -P.I. (Internal competitive university funding)
  • Lin D, Clarke SL, Narasaraju T. β,β-carotene 9’, 10’-oxygenase 2 (BCO2) in influenza virus pneumonia. NIH P20GM103648, July 1, 2015-June 30, 2016. -P.I.
  • Lin D, Yao WX. Egg lutein and inflammation. American Egg Nutrition Center, Nov. 1, 2013-Oct. 31, 2015. -P.I.
  • Lin D. Food bioactive compounds in chronic disease prevention. OSU/NSCI Faculty Start-up Grant. Aug. 1, 2013-Dec. 30, 2014. -P.I.
  • Lin D. Dietary supplements protect retinal pigment epithelial cells from apoptosis. NIH P20 RR017686, July 1, 2008-June 30, 2012 (no-cost extension to June 30, 2013). -P.I.
  • Lin D. Supplemental equipment award (to purchase ERG system). NIH P20 RR017686, July 1, 2008-June 30, 2010. -P.I.
  • Lin D. Wolfberry phytochemicals in the prevention of leukemia. KSU Johnson Cancer Center Innovative Research Award. 1- Dec. 31, 2010. -P.I.
  • Lin D. Cellometer auto cell counter. KSU Johnson Cancer Center Equipment Award. May 1- Aug. 30, 2010. -P.I.
  • Lin D. The role of gap junctions in oxidative neurodegeneration in the cerebellum. NIH P20 RR016475 from the INBRE Program of the National Center for Research Resources, Sep. 15, 2007-April 30, 2009. -P.I.
  • Lin D, Takemoto D. Mutations of protein kinase C gamma in spinocerebellar ataxia cause altered cell gap junctional communication, National Organization for Rare Disorders (NORD), USA. 15, 2004-Oct. 14, 2006. -P.I.

Professional Memberships:

  • Member- Society for Experimental Biology and Medicine (2016-) 

  • Member- American Society for Nutrition (2008-) 

  • Member- North America Chinese Society for Nutrition (2013-)

  • Member- American Association for the Advancement of Science 

  • Member- Association for Research in Vision and Ophthalmology 

  • Member- American Society for Cell Biology

  • Member- Society for Neuroscience 

Service:

          Department Service
  • NSCI GTA award committee, Sp2018

  • University Graduate Faculty Group One NSCI representative

  • NSCI Nutrigenomics Curriculum Development Committee (Spring 2016)

  • NSCI DGF and GSF (Graduate Summer Fellowship Selection committee (Spring 2016)

  • NSCI Curriculum Committee (Fall 2013- Spring 2014)

    University Service

  • Women’s Faculty Council Research Award Reviewer, Spring 2018

  • OSU IACUC committee (Jan. 1, 2015-present)

  • Judge, 2017 OSU Virtual Research Poster Symposium (spring 2017)

  • OSU Faculty Council Budget Committee (Fall 2016-) 

  • NSCI one time committee to select the candidates for Graduate Summer Dissertation Fellowship and Distinguished Graduate Fellowship, Spring 2016

  • OSU Biological Sciences Graduate Faculty Group I Committee (NSCI Representative, Spring 2014-present 

  • Pre-health Advisory Committee, Spring 2015-Spring 2017

  • OSU Biological Sciences Graduate Faculty Group I Bylaws Committee (Spring 2014-Spring 2015)

  • OSU Research Week Symposium Feb. 2014, 2015, 2016, Judge (paper and poster)

     Professional Service 

  • Member, Literature Selection Technical Review Committee, NIH/NLM, July 2018-June 2022

  • Review Panel for the Prestigious Programs of the National Natural Science Foundation of China, April 2017 

  • USDA NIFA program review panel, October 2016 and October 2017

  • Board member 2015-2016, NACSN (North America Chinese Society for Nutrition)

  • Expert group member, Chinese Grain and Oil Association (2015-present) 

  • Judge, Conrad Foundation, 2014 Spirit of Innovation Challenge 

  • Judge, Poster competition, Experimental Biology 2011-2015 

    Editorial member and Ad hoc manuscript reviewers 

  • Editorial Board, Journal of Nutritional Biochemistry (2018-)

  • Editorial Board, Journal of Human Nutrition and Food Science 

  • Journal of Agricultural and Food Chemistry

  • Experimental Biology and Medicine

  • Biomedicine & Pharmacotherapy (2017-)

  • International Journal of Molecular Sciences 

  • Animal Science Journal

  • Nutrition & Diabetes

  • Journal of Nutritional Biochemistry

  • Journal of Nutrition

  • Lipids

  • Journal of Medicinal Food 

  • Oncotarget

  • Molecular Nutrition and Food Research

  • Journal of Cellular and Molecular Medicine 

  • Evidence-based Complementary and Alternative Medicine    

  • International Journal of Biochemistry & Cell Biology

  • Biosensors 

  • Phytotherapy Research

  • Journal of Biomedical Science

  • Inflammation

  • Journal of Cell Science

  • PLOS ONE

  • Nutrients 

  • Journal of Proteomics 

  • Journal of Proteome Research 

  • Journal of Nutrition, Health and Aging 

  • Experimental Physiology

  • Journal of Cancer Research and Therapy

  • Food and Function 

  • BMC Complementary and Alternative Medicine

  • Cell Proliferation

  • Journal of Veterinary Science and Technology

  • Environmental Toxicology and Pharmacology

  • Life Science

  • Journal of Nutrition and Food Sciences

  • Pharmaceutical Crops

  • Medical Hypotheses

  • International Journal of Nutrition and Metabolism

  • Biophysical Review & Letters

  • International Journal of Medical Sciences

  • American Journal of Alzheimer’s Disease & Other Dementias

  • Current Eye Research

  • Molecular Vision